| 8 February
| Terry Speed | WEHI Bioinformatics |
| 15 February
| No Seminar | Lorne Genome |
| 22 February
| James Fu | WEHI Bioinformatics |
| 1 March
| Xueyi Dong | WEHI Epigenetics and Development |
| 8 March
| Mirana Ramialison | MCRI / Monash University (ARMI) |
| 15 March
| Mike Clark | University of Melbourne |
| 22 March
| Felicity Newell | QIMR |
| 29 March
| Kristen Feher | WEHI Bioinformatics |
| 5 April
| Belinda Phipson | WEHI Bioinformatics |
| 12 April
| Nadia Davidson | WEHI Bioinformatics/Blood Cells and Blood Cancer |
| 19 April
| No Seminar | Easter Tuesday |
| 26 April
| No Seminar | Cancelled Seminar |
| 3 May
| Ellis Patrick | University of Sydney |
| 10 May
| Jarryd Martin | WEHI Bioinformatics |
| 17 May
| Marie Trussart | WEHI Bioinformatics |
| 24 May
| Chris Woodruff | WEHI Bioinformatics |
| 31 May
| Goknur Giner | WEHI Bioinformatics/Blood Cells and Blood Cancer |
| 7 June
| Sam Lee | WEHI Bioinformatics |
| 14 June
| Lan Nguyen | Monash University |
| 21 June
| Elisa Roesti | WEHI Bioinformatics |
| 28 June
| Hannah Coughlan | WEHI Bioinformatics |
| 5 July
| Tim Peters | Garvan Institute |
| 12 July
| Andy Yunshun Chen | WEHI Bioinformatics / Cancer and Stem Cells |
| 19 July
| Stefano Mangiola | WEHI Bioinformatics |
| 26 July
| Jinjin Chen | WEHI Bioinformatics |
| 2 August
| Shila Ghazanfar | University of Sydney |
| 9 August
| Chin Wee Tan | WEHI Bioinformatics |
| 16 August
| Jimmy Breen | Telethon Kids Institute |
| 23 August
| Gordon Smyth | WEHI Bioinformatics |
| 30 August
| Dharmesh Bhuva | WEHI Bioinformatics |
| 6 September
| Katherine Pillman | Centre for Cancer Biology (Uni SA) |
| 13 September
| Alan Rubin | WEHI Bioinformatics |
| 20 September
| Jianan Wang | WEHI Bioinformatics |
| 27 September
| Holly Whitfield | WEHI Bioinformatics |
| 4 October
| Mengbo Li | WEHI Bioinformatics |
| 11 October
| Ramyar Molania | WEHI Bioinformatics |
| 18 October
| Jinming Cheng | WEHI Bioinformatics |
| 25 October
| Ning Liu | WEHI Bioinformatics |
| 1 November
| No Seminar | AGTA |
| 8 November
| Ahmed Mohamed | WEHI Bioinformatics |
| 15 November
| Junli Nie | WEHI Bioinformatics |
| 22 November
| Pedro Baldoni | WEHI Bioinformatics |
| 29 November
| No Seminar | ABACBS 2022 (November 29 - December 2) |
| 6 December
| Yimin Zhang | WEHI Bioinformatics |
| 13 December
| Justin Bedo | WEHI Bioinformatics |