limmaGUI is a Graphical User Interface for Gordon Smyth's limma package (Linear
Models for MicroArray data). It uses state-of-the-art statistical
techniques to normalize microarray data, perform diagnostic plots
and to find differentially expressed genes in complex
experimental designs. limma and limmaGUI are both R packages. The limma package offers R
users a command-line interface. The limmaGUI package, while not as
powerful as limma to the expert user, offers a simple
point-and-click interface to many of the commonly-used limma
In order to use limmaGUI, you need to have R 1.9.0 or later,
Tcl/Tk 8.3 or
later (ActiveTcl for
X11 Tcl/Tk for MacOSX or an appropriate Linux
either from source or by a package manager e.g. RPM), including
the Tktable and
extensions, both of which come with
You also need the
limma, limmaGUI, sma,
tkrplot, R2HTML and xtable R packages. The limma package is
available on Bioconductor
(Click on Release 1.3 packages), the limmaGUI package is available
and the other packages are available from CRAN. limmaGUI has been
succesfully tested on Windows 2000, Windows XP, and Red Hat Linux,
and on Mac OSX with X11.
Some screenshots from limmaGUI
The Weaver data set...
Differentially Expressed Genes from the Swirl Data Set...
Comments/Questions? Contact firstname.lastname@example.org.
23 June 2003