Rank	ID	GeneSet	BroadUrl	Description	PubMedID	NumGenes	Contributor	Ontology	GOID	p.value	p.adj	vote.rank	avg.rank	med.rank	min.pvalue	min.rank	avg.logfc	avg.logfc.dir	direction	significance
1	M17752	GO_PROTON_TRANSPORTING_V_TYPE_ATPASE_COMPLEX	http://www.broadinstitute.org/gsea/msigdb/cards/GO_PROTON_TRANSPORTING_V_TYPE_ATPASE_COMPLEX.html	A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.		19/23	Gene Ontology	CC	GO:0033176	6.46193172008854e-07	5.7759728144176e-06	10	175.212121212121	41	1.95816174080302e-08	1	1.25144510294311	-1.1589645928754	-1	3.06615536902895
2	M17227	GO_ACTIN_FILAMENT_BUNDLE	http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTIN_FILAMENT_BUNDLE.html	An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.		83/106	Gene Ontology	CC	GO:0032432	1.94334692773781e-06	9.6320650041945e-06	30	162.060606060606	50	5.88893563278065e-08	17	2.00960850518039	2.07930767999163	1	5.20279840693455
3	M17676	GO_NEUROMUSCULAR_JUNCTION	http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEUROMUSCULAR_JUNCTION.html	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.		91/122	Gene Ontology	CC	GO:0031594	8.27671335159808e-11	1.29966769115635e-09	30	114.636363636364	51	2.50809495513038e-12	7	2.15743801556458	2.40257928589378	1	8.53779633917546
4	M17707	GO_AP_TYPE_MEMBRANE_COAT_ADAPTOR_COMPLEX	http://www.broadinstitute.org/gsea/msigdb/cards/GO_AP_TYPE_MEMBRANE_COAT_ADAPTOR_COMPLEX.html	Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).		42/45	Gene Ontology	CC	GO:0030119	9.09948701884598e-06	2.05712138441615e-05	55	138	57	2.7574324742007e-07	3	1.12729842955919	-1.15625910417918	-1	2.87518003096895
5	M17336	GO_CONTRACTILE_FIBER	http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONTRACTILE_FIBER.html	Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.		205/299	Gene Ontology	CC	GO:0043292	7.25122666575084e-09	9.7975876576773e-08	25	180.454545454545	64	2.19734142158918e-10	15	2.00611102184456	1.42167103817656	0.333333333333333	6.38009515234171
6	M17217	GO_INTERMEDIATE_FILAMENT	http://www.broadinstitute.org/gsea/msigdb/cards/GO_INTERMEDIATE_FILAMENT.html	A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.		81/224	Gene Ontology	CC	GO:0005882	6.77072753758143e-13	1.51299719205185e-11	35	180.939393939394	68	2.05173561744959e-14	12	2.74609384517935	1.53514173074482	0.333333333333333	14.0283768621364
7	M17059	GO_LATE_ENDOSOME_MEMBRANE	http://www.broadinstitute.org/gsea/msigdb/cards/GO_LATE_ENDOSOME_MEMBRANE.html	The lipid bilayer surrounding a late endosome.		110/129	Gene Ontology	CC	GO:0031902	1.2549492372644e-06	8.94060150277647e-06	25	167.69696969697	68	3.80287879045983e-08	1	1.17485511651853	-1.06349080912668	-1	3.23365060120515
8	M17381	GO_CLATHRIN_VESICLE_COAT	http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_VESICLE_COAT.html	A clathrin coat found on a vesicle.		29/32	Gene Ontology	CC	GO:0030125	2.11415111916543e-06	9.75717711512718e-06	70	142.909090909091	70	6.40652510989145e-08	10	1.38528889885835	-1.46800970512785	-1	3.76976577781915
9	M17616	GO_ENDOPLASMIC_RETICULUM_QUALITY_CONTROL_COMPARTMENT	http://www.broadinstitute.org/gsea/msigdb/cards/GO_ENDOPLASMIC_RETICULUM_QUALITY_CONTROL_COMPARTMENT.html	A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins.		14/15	Gene Ontology	CC	GO:0044322	9.02182854277224e-05	0.000131042059583767	105	156.515151515152	75	2.73400703053609e-06	9	1.0648691492848	-1.05051365810185	-1	2.36791871935439
10	M17598	GO_MICROTUBULE_END	http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_END.html	Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end.		27/27	Gene Ontology	CC	GO:1990752	1.0775204970947e-05	2.38037798027384e-05	30	154.636363636364	76	3.26523068627243e-07	15	1.55090872565977	0.641658760211241	0.333333333333333	3.43930852644594
11	M17465	GO_APICOLATERAL_PLASMA_MEMBRANE	http://www.broadinstitute.org/gsea/msigdb/cards/GO_APICOLATERAL_PLASMA_MEMBRANE.html	The apical end of the lateral plasma membrane of epithelial cells.		23/27	Gene Ontology	CC	GO:0016327	9.60928692313317e-07	7.88306588621377e-06	10	183.939393939394	78	2.91190648489367e-08	4	2.94159074755607	-3.16837777537092	-1	7.14700630278383
12	M17816	GO_CLATHRIN_ADAPTOR_COMPLEX	http://www.broadinstitute.org/gsea/msigdb/cards/GO_CLATHRIN_ADAPTOR_COMPLEX.html	A membrane coat adaptor complex that links clathrin to a membrane.		31/34	Gene Ontology	CC	GO:0030131	1.13504832934138e-06	8.56445557593947e-06	130	112.242424242424	78	3.43954228481508e-08	6	1.21545109533092	-1.2994849776898	-1	3.41226637482991
13	M17201	GO_IONOTROPIC_GLUTAMATE_RECEPTOR_COMPLEX	http://www.broadinstitute.org/gsea/msigdb/cards/GO_IONOTROPIC_GLUTAMATE_RECEPTOR_COMPLEX.html	A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.		32/56	Gene Ontology	CC	GO:0008328	4.70269663193231e-06	1.35933668813566e-05	50	155.69696969697	79	1.42506283471578e-07	11	2.18246608456154	1.35111908857759	0.333333333333333	6.23329137040306
14	M16979	GO_I_BAND	http://www.broadinstitute.org/gsea/msigdb/cards/GO_I_BAND.html	A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.		134/198	Gene Ontology	CC	GO:0031674	4.95479324869914e-08	5.53602861056577e-07	85	179.060606060606	79	1.50145253567555e-09	8	2.07579114006721	1.64557117251293	0.333333333333333	5.88110198430113
15	M17391	GO_MICROTUBULE_PLUS_END	http://www.broadinstitute.org/gsea/msigdb/cards/GO_MICROTUBULE_PLUS_END.html	The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.		22/22	Gene Ontology	CC	GO:0035371	5.36888476685165e-06	1.4713783252551e-05	45	159.636363636364	81	1.6269390129156e-07	13	1.60372308897909	0.63722512262292	0.333333333333333	4.34677557011062
16	M17516	GO_CONDENSED_CHROMOSOME_OUTER_KINETOCHORE	http://www.broadinstitute.org/gsea/msigdb/cards/GO_CONDENSED_CHROMOSOME_OUTER_KINETOCHORE.html	The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.		14/14	Gene Ontology	CC	GO:0000940	1.20865903526503e-05	2.56288649448534e-05	5	199.575757575758	83	3.66262460079587e-07	1	2.14612985393063	2.14612985393063	1	4.75166745152965
17	M17848	GO_VACUOLAR_MEMBRANE	http://www.broadinstitute.org/gsea/msigdb/cards/GO_VACUOLAR_MEMBRANE.html	The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.		648/795	Gene Ontology	CC	GO:0005774	1.65278362715494e-06	8.94060150277647e-06	60	206.272727272727	83	5.50928315824998e-08	2	1.38476569587961	-1.26065629664566	-1	3.32268152304213
18	M17016	GO_FILOPODIUM_MEMBRANE	http://www.broadinstitute.org/gsea/msigdb/cards/GO_FILOPODIUM_MEMBRANE.html	The portion of the plasma membrane surrounding a filopodium.		19/22	Gene Ontology	CC	GO:0031527	3.89834601675466e-06	1.2204634516605e-05	35	93.7272727272727	83	1.18131920759552e-07	10	2.40663101641362	2.58062563016736	1	6.26241267166055
19	M17433	GO_CELL_CELL_ADHERENS_JUNCTION	http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CELL_ADHERENS_JUNCTION.html	An adherens junction which connects a cell to another cell.		68/93	Gene Ontology	CC	GO:0005913	4.09547302165935e-08	4.6656271089884e-07	15	212.69696969697	85	1.24105245544925e-09	11	2.26943741655995	2.56035590018493	1	6.78114702053386
20	M17284	GO_ACTOMYOSIN	http://www.broadinstitute.org/gsea/msigdb/cards/GO_ACTOMYOSIN.html	Any complex of actin, myosin, and accessory proteins.		93/116	Gene Ontology	CC	GO:0042641	5.17866271704734e-06	1.44480370531601e-05	70	171	86	1.56929567273445e-07	12	1.87697024019308	2.01563390813146	1	4.71983790323985