Rank ID GeneSet BroadUrl Description PubMedID NumGenes Contributor Ontology GOID p.value p.adj vote.rank avg.rank med.rank min.pvalue min.rank avg.logfc avg.logfc.dir direction significance 1 M11591 GO_IRON_ION_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/GO_IRON_ION_TRANSPORT.html The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 52/73 Gene Ontology BP GO:0006826 5.28374705415904e-08 5.26363451554198e-07 5 1153.06060606061 78 1.60113551197544e-09 1 1.49090229494169 -0.770934935687056 -0.333333333333333 9.95418696067034 2 M11113 GO_FERRIC_IRON_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/GO_FERRIC_IRON_TRANSPORT.html The directed movement of ferric iron (Fe(III) or Fe3+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 36/44 Gene Ontology BP GO:0015682 3.72852682664492e-08 4.7792934777903e-07 5 1474.09090909091 98 1.12985663456004e-09 2 1.4488872608747 -0.746344538989784 -0.333333333333333 9.15042829664248 3 M16469 GO_TRIVALENT_INORGANIC_CATION_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRIVALENT_INORGANIC_CATION_TRANSPORT.html The directed movement of inorganic cations with a valency of three into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage. 36/44 Gene Ontology BP GO:0072512 3.72852682664492e-08 4.7792934777903e-07 5 1478.54545454545 99 1.12985663456004e-09 3 1.4488872608747 -0.746344538989784 -0.333333333333333 9.15042829664248 4 M15608 GO_NEURON_PROJECTION_GUIDANCE http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_PROJECTION_GUIDANCE.html The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues. 211/347 Gene Ontology BP GO:0097485 1.00941947755885e-19 9.58536495730883e-18 85 777.878787878788 108 3.05884690169348e-21 15 2.27154373755058 2.45471993039839 1 42.4487959078466 5 M16285 GO_MESONEPHROS_DEVELOPMENT http://www.broadinstitute.org/gsea/msigdb/cards/GO_MESONEPHROS_DEVELOPMENT.html The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney. 91/129 Gene Ontology BP GO:0001823 2.43647252147864e-11 5.89094718885677e-10 100 1034.90909090909 138 7.38325006517401e-13 26 2.33048218116511 2.61851645632274 1 25.8625737988756 6 M10489 GO_SYNAPSE_ORGANIZATION http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPSE_ORGANIZATION.html A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). 204/264 Gene Ontology BP GO:0050808 9.0283305424171e-34 1.40029406712889e-30 55 669.030303030303 147 2.73585774012641e-35 1 2.34458881102129 2.47631249256221 1 64.8784389870562 7 M13107 GO_REGULATION_OF_SYNAPSE_ORGANIZATION http://www.broadinstitute.org/gsea/msigdb/cards/GO_REGULATION_OF_SYNAPSE_ORGANIZATION.html Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). 124/183 Gene Ontology BP GO:0050807 3.03580193153702e-15 1.48690383025703e-13 165 708.575757575758 162 9.19939979253644e-17 31 2.45455234506339 2.51856948433465 1 37.8615067497107 8 M13463 GO_MEMBRANE_DEPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL http://www.broadinstitute.org/gsea/msigdb/cards/GO_MEMBRANE_DEPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL.html The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. 21/39 Gene Ontology BP GO:0086012 7.77082845130788e-09 1.17395015532258e-07 10 1509.69696969697 175 2.35479650926842e-10 4 2.94081677712329 2.41410532991763 0.333333333333333 22.445044342808 9 M15681 GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES http://www.broadinstitute.org/gsea/msigdb/cards/GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES.html The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell. 122/181 Gene Ontology BP GO:0007156 1.16788382942092e-19 1.0868326916591e-17 90 1394.84848484848 178 3.53904190733612e-21 13 2.58779827675679 2.58578281260774 1 47.1014721613428 10 M12483 GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION.html Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration. 28/34 Gene Ontology BP GO:0014912 1.03957027995337e-07 5.26363451554198e-07 20 1057.72727272727 194 3.15021312833716e-09 19 2.58877279176176 2.78473888345303 1 17.0550432362753 11 M16902 GO_SYNAPSE_ASSEMBLY http://www.broadinstitute.org/gsea/msigdb/cards/GO_SYNAPSE_ASSEMBLY.html The aggregation, arrangement and bonding together of a set of components to form a synapse. 90/123 Gene Ontology BP GO:0007416 1.22496520457154e-14 5.18160281533761e-13 125 691.787878787879 195 3.71201577142891e-16 11 2.31187807883236 2.33142665199744 1 26.4180252646889 12 M13718 GO_CARDIAC_VENTRICLE_DEVELOPMENT http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_VENTRICLE_DEVELOPMENT.html The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. 139/191 Gene Ontology BP GO:0003231 1.89487676052256e-13 6.43566537716167e-12 205 687.030303030303 202 5.74205078946283e-15 4 2.27580987246958 2.56411234490181 1 26.4267877601618 13 M16150 GO_CARDIAC_CONDUCTION http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_CONDUCTION.html Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles. 74/127 Gene Ontology BP GO:0061337 3.33295200518624e-13 1.09212856902335e-11 75 1354.57575757576 206 1.0099854561172e-14 25 2.4726603270691 1.77256721898809 0.333333333333333 27.0510311572005 14 M10755 GO_TRANSITION_METAL_ION_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/GO_TRANSITION_METAL_ION_TRANSPORT.html The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. 87/122 Gene Ontology BP GO:0000041 5.46617225973963e-08 5.26363451554198e-07 15 1812.63636363636 206 1.65641588018415e-09 9 1.47126414082852 -0.738421227936045 -0.333333333333333 9.02652219858172 15 M16833 GO_CARDIAC_CELL_DEVELOPMENT http://www.broadinstitute.org/gsea/msigdb/cards/GO_CARDIAC_CELL_DEVELOPMENT.html The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual. 59/93 Gene Ontology BP GO:0055006 6.04755372050294e-11 1.37264719324391e-09 205 941.363636363636 209 1.83259203656977e-12 1 2.52678930631243 2.72350932591263 1 21.9032627572271 16 M12499 GO_SPROUTING_ANGIOGENESIS http://www.broadinstitute.org/gsea/msigdb/cards/GO_SPROUTING_ANGIOGENESIS.html The extension of new blood vessels from existing capillaries into avascular tissues resulting from the proliferation of blood vessel endothelial cells. 69/83 Gene Ontology BP GO:0002040 5.82151003401728e-09 9.05935992919144e-08 130 1025.9696969697 218 1.76409395468145e-10 30 2.34223309740801 2.37934097106016 1 18.6981219323599 17 M13356 GO_CELL_CELL_SIGNALING_INVOLVED_IN_CARDIAC_CONDUCTION http://www.broadinstitute.org/gsea/msigdb/cards/GO_CELL_CELL_SIGNALING_INVOLVED_IN_CARDIAC_CONDUCTION.html Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium. 25/46 Gene Ontology BP GO:0086019 8.00777931403721e-11 1.79130368530352e-09 20 1149.57575757576 232 2.4265997922267e-12 20 3.03777869019784 2.30294075716923 0.333333333333333 28.6149353704708 18 M11839 GO_AMEBOIDAL_TYPE_CELL_MIGRATION http://www.broadinstitute.org/gsea/msigdb/cards/GO_AMEBOIDAL_TYPE_CELL_MIGRATION.html Cell migration that is accomplished by extension and retraction of a pseudopodium. 192/270 Gene Ontology BP GO:0001667 5.09011556002805e-13 1.60029106086558e-11 70 1159.78787878788 243 1.54245926061494e-14 15 2.05600539316086 1.31884966459898 0.333333333333333 25.4243448161645 19 M10326 GO_NEURON_RECOGNITION http://www.broadinstitute.org/gsea/msigdb/cards/GO_NEURON_RECOGNITION.html The process in which a neuronal cell in a multicellular organism interprets its surroundings. 43/63 Gene Ontology BP GO:0008038 4.99958781868987e-08 5.26363451554198e-07 110 896.242424242424 247 1.51502664844909e-09 33 2.64779500484601 2.74126645246007 1 20.9163978020175 20 M16895 GO_RECEPTOR_CLUSTERING http://www.broadinstitute.org/gsea/msigdb/cards/GO_RECEPTOR_CLUSTERING.html The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response. 49/64 Gene Ontology BP GO:0043113 1.03435669069446e-07 5.26363451554198e-07 70 1089.72727272727 262 3.13441437141849e-09 39 2.06421177438838 2.24781734085024 1 14.210013018027