This R package is designed for performing GO analysis on RNA-seq data, accounting for the selection bias effects inherent to this platform. It can also be used to perform other category based tests, such as KEGG pathway analysis. For more information see the cited article below, or the package documentation.
GOseq is now available as a package from bioconductor. The latest release as well as up to date documentation can be obtained directly from bioconductor package goseq.
CitationTo reference GOseq, please cite:
Gene ontology analysis for RNA-seq: accounting for selection bias
Matthew D. Young, Matthew J. Wakefield, Gordon K. Smyth, Alicia Oshlack
Genome Biology 2010, 11:R14 (4 February 2010)