GRIDSS - Genomic Rearrangement IDentification Software Suite

GRIDSS a modular software suite containing tools useful for the detection genomic rearrangements. GRIDSS includes a genome-wide break-end assembler, as well as a structural variation caller for i Illumina sequencing data. GRIDSS calls variants based on alignment-guided positional de Bruijn graph genome-wide break-end assembly, split read, and read pair evidence.

GRIDSS won the ICGC/TCGA Dream Mutation Calling Challenge #5 SV Sub-challenge in 2015 and is highest ranked as a late entry in the 2014 challenge.

GRIDSS is described in a preprint and currently under review.

GRIDSS is available from Github.