Tim Beißbarth's Home Page

Short Vita:

• Since 2.2005: Scientist at the Molecular Genome Analysis department at German Cancer Research Center - DKFZ.
• 2002-2005: Scientist at the Bioinformatics Department at Walter and Eliza Hall Institute of Medical Research, Melbourne - WEHI.
• 2001-2002 Scientist at:
  Computational Molecular Biology - Max-Planck-Institut Molecular Genetics, Berlin
  Functional Genome Analysis - German Cancer Research Center, Heidelberg
  
• 6.2001/2002: Teaching of Bioinformatics courses at the Akademie fuer Weiterbildung.
• 1998-2001: PhD thesis at the German Cancer Research Center - DKFZ
  Departments: Theoretical Bioinformatics and Molecular Biology of the Cell I
• 1996-1998: Diplom (Masters) thesis in the Department of Cell Genetics about MHC Class I - TAP interaction
• 1996: Assistant in Biochemical Practical Cources at the Institute for Biochemistry
• 1995-1996: Worked at the Regional Computing Center - Object Oriented Programming, Courses
• 1992-1997: Study of Biology at the University of Cologne
• 1989-1990: West Valley Highschool - Cottonwood, CA, USA
• 1983-1992: Heinrich-Heine-Gymnasiums - Cologne, Germany
• Sept. 8., 1972: Born in Cologne, Germany

Degrees:

• Diploma (Masters) in Biology - 1.1998
  University of Cologne. Subjects: Genetics, Biochemistry, Informatics. (Mark: 1.0)
  Thesis (German): "Interaktion von MHC-Klasse-I mit dem Peptidtransporter TAP -
  Characterisierung von HLA-A2 Mutanten in der lymphoblastoiden Cellinie C1R"
• PhD in Biology (Dr. rer nat) - 11.2001
  Biology faculty, University Heidelberg (Mark: 1.0)
  Thesis (English): "Analysis of transcription factor CREM dependent gene expression during mouse spermatogenesis"

Publications

• Increased Efficiency of Folding and Peptide Loading of Mutant MHC Class I Molecules;
  Beissbarth T, Sun J, Kavathas PB, Ortmann B
  European Journal of Immunology; 4.2000; 30(4): 1203-1213.
  Paper Alert in Current Opinion in Immunology 2000, 12: 355-364.
• Processing and quality control of DNA array hybridization data
  Beissbarth T, Fellenberg K, Brors B, Arribas-Prat R, Boer JM, Hauser NC, Scheideler M,
  Hoheisel JD, Schuetz G, Poustka A, Vingron M
  Bioinformatics; 11.2000; 16(11): 1014-1022.
• GeneNest: automated generation and visualization of gene indices
  Haas S, Beissbarth T, Rivals E, Krause A, Vingron M
  Trends in Genetics; 11.2000; 16(11): 521-523
• Monitoring the switch from housekeeping to pathogen defence metabolism in Arabidopsis thaliana using cDNA arrays
  Scheideler M, Schlaich NL, Fellenberg K, Beissbarth T, Hauser NC, Vingron M, Slusarenko AJ, Hoheisel JD
  Journal of Biological Chemistry; 3.2002; 277(12): 10555-10561.
• Analysis of CREM-dependent gene expression during mouse spermatogenesis
  Beissbarth T, Borisevich I, Hoerlein A, Kenzelmann M, Hergenhahn M, Klewe-Nebenius A, Klaeren R, Korn B, Schmid W, Vingron M, Schuetz G
  Molecular and Cellular Endocrinology; 12.2003; 212(1-2): 29-39.
• GOstat: Find statistically overrepresented Gene Ontologies within a group of genes
  Beissbarth T, Speed TP
  Bioinformatics, 6.2004; 20(9): 1464-1465.
• Statistical modeling of sequencing errors in SAGE libraries
  Beissbarth T, Hyde L, Smyth GK, Job C, Boon WM, Tan SS, Scott HS, Speed TP
  Bioinformatics; 7.2004; 20(ISMB Supplement 1), I31-I39.
• A comparative analysis of transcribed genes in the mouse hypothalamus and neocortex reveals chromosomal clustering
  Boon WM, Beissbarth T, Hyde L, Smyth GK, Gunnersen J, Denton DA, Scott HS, Tan SS
  Proc Natl Acad Sci USA; 10.2004; 101(21); 14972-14977.
• A systematic approach for comprehensive T-cell epitope discovery using peptide libraries.
  Beissbarth T, Tye-Din JA, Smyth GK, Speed TP, Anderson RP
  Bioinformatics; 7.2005; 21(ISMB Supplement 1), in press.

Other Documents

• How does the Transporter associated with Antigen Processing influence folding and assembly of MHC class I molecules.
  Slides
• Transcription Profiling using DNA Array Data
  Poster
• How to arrange gene expression profiles in linear order
  Poster
• Correspondence Analysis, Gene Ontologies and microarray data.
  Poster
• GOstat - Find statistically overrepresented Gene Ontologies within a group of genes
  Poster
• Identification of putative transcription factor binding sites conserved across othologous human, mouse and rat sequences
  Poster

Address

Tim Beißbarth - Last Change: 01.March.2005