Bioinformatics Seminars

Bioinformatics Seminar

Time: 11:00am Tuesdays.
Zoom Webinar

9 March 2021

An application of spatial statistics to live cell imaging data

Jack Hywood
Dorevitch Pathology

The striking phenomenon of collective motion is important in many biological systems. It underlies processes in developmental biology and the immune system, where cells must quickly localize at specific locations. Live cell imaging is increasingly being used to probe the mechanisms behind these processes, capturing cell movements in real time. We present here an example of a novel combination of spatial statistics and functional data analysis in the analysis of live cell imaging. We demonstrate how these methods can be used to measure cell aggregation, applying these methods to an experiment of T cells engaging a tumouroid.

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