Bioinformatics Seminar
Time:
Venue: Na
10 November 2020
NaUnderstanding Information Flow Using Network-based Analysis of Phosphoproteomic Data
Hannah HuckstepWEHI Bioinformatics
Protein phosphorylation is one of the best known post-translational mechanisms playing a key role in the regulation of cellular processes. However data saturation is occurring and the bottleneck of assigning biologically relevant functionality to phosphosites needs to be addressed. In this talk I will first compare and contrast the global proteomics and phosphoproteomics coverage of current popular public knowledgbases. Second ; I will introduce a resource I have been developing throughout my PhD that utilises two of these knowledgebases and demonstrate how it can be used in the analysis of phosphoproteomics data.