Bioinformatics Seminar
Time:
Venue: Na
5 April 2016
NaVisual inference for Q-Q plots
Heike HofmannIowa State University
In statistical modeling we strive to specify models that resemble data collected in studies or observed from processes. Consequently ; distributional specification and parameter estimation are central to parametric models. Graphical procedures ; such as the quantile-quantile (Q-Q) plot ; are a widely used method of distributional assessment ; though critics find their interpretation to be overly subjective. Formal goodness-of-fit tests are available and are quite powerful ; but only indicate whether there is a lack of fit ; not why there is lack of fit. In this talk we explore the use of the lineup protocol to inject rigor into graphical distributional assessment and compare its power to that of formal distributional tests. We find that lineup tests are considerably more powerful than traditional tests of normality. A further investigation into the design of Q-Q plots shows that de-trended Q-Q plots are more powerful than the standard approach as long as the plot preserves distances in x and y to be the same. While we focus on diagnosing non-normality ; our approach is general and can be directly extended to the assessment of other distributions.;