Current Bioinformatics Seminar
10:45am Tuesdays in Rooms B/C on the 7th floor at WEHI
23 March 2010
Microarray studies on severe malaria
Charity LawWEHI Bioinformatics
Cerebral malaria causes inflammation of the brain, where most infected individuals fall into a coma. Here we explore, through the use of microarrays, unsupervised clustering and semi-supervised clustering, the mechanisms by which the immunomodulatory drug known as Drug-1018 protects mice from cerebral malaria. Another type of severe malaria is severe malarial anemia. We make use of microarray data from human bone marrow RNA to better understand erythropoiesis in the presence of severe malarial anemia.