Bioinformatics Seminars

Current Bioinformatics Seminar

23 October 2018

plyranges: A grammar of genomic data transformation

Stuart Lee
WEHI Molecular Medicine

Most bioinformatics software research is focussed on algorithmic developments; we require our methods to be fast, accurate, and memory efficient. There is another aspect that can affect the quality and output of our methods: the user. The usability of software can dramatically affect results, so keeping the human user in mind when designing software is important.

In this talk I will discuss the design and implementation of my Bioconductor/R package plyranges which is a domain specific language (DSL) for genomic data analysis. The aim of plyranges is to enable users to write 'human readable' analysis code. I will show several vignettes of using plyranges to explore data from the Human Epigenomics Roadmap project and understanding intron signal in RNA-seq data.

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